Focal Aβ-amyloid deposition precedes cerebral microbleeds and Superficial siderosis: a case report
نویسندگان
چکیده
1CSIRO Preventative Health National Research Flagship, Australian e-Health Research CentreBioMedIA, Brisbane, QLD, Australia 2Department of Radiology, University of Melbourne and the Royal Melbourne Hospital, Melbourne, VIC, Australia 3Department of Molecular Imaging & Therapy, Austin Health, Melbourne, VIC, Australia 4Department of Aged Care, Austin Health, Melbourne, VIC, Australia 5The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia 6Department of Medicine, Austin Health, University of Melbourne, VIC, Australia
منابع مشابه
Diagnostic Significance of Cortical Superficial Siderosis for Alzheimer Disease in Patients with Cognitive Impairment.
BACKGROUND AND PURPOSE Because the diagnostic significance of cortical superficial siderosis for Alzheimer disease and the association between cortical superficial siderosis and the topographic distribution of cerebral microbleeds have been unclear, we investigated the association between cortical superficial siderosis and clinicoradiologic characteristics of patients with cognitive impairment....
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BACKGROUND AND PURPOSE Transient focal neurological episodes occur in cerebral amyloid angiopathy (CAA) and can mimic transient ischemic attack (TIA). Risk factors and outcomes of minor ischemic stroke or TIA might differ in patients with and without cerebral microbleeds (CMBs), including CAA-consistent lobar CMB. METHODS Baseline magnetic resonance imaging (MRI) was analyzed for CMBs and cor...
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Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition and is classified into several types according to the amyloid protein involved. Of these, sporadic amyloid β-protein (Aβ)-type CAA is most commonly found in older individuals and in patients with Alzheimer's disease (AD). Cerebrovascular Aβ deposits accompany functional and pathological changes in cerebral blood vesse...
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BACKGROUND AND PURPOSE Validation of the Boston criteria for the in vivo diagnosis of cerebral amyloid angiopathy (CAA) is challenging, because noninvasive diagnostic tests do not exist. Hereditary cerebral hemorrhage with amyloidosis-Dutch type is an accepted monogenetic model of CAA and diagnosis can be made with certainty based on DNA analysis. The aim of this study was to analyze and refine...
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